[Project summary in Français / Português]
Scientific title: IMPACT 2: Monitoring Interventions to Improve ACT Access and Targeting
Scroll down for a list of publications about the findings of this study, and a policy brief.
It is generally agreed that artemisinin-based combination therapies (ACT) are the best treatment for malaria, but it is less clear how it should be deployed by national programmes. Some countries have started to improve this process, on the one hand, by making ACTs more accessible to patients and, on the other hand, by targeting ACTs more effectively to patients who have malaria.
The government of Tanzania has addressed both ACT access and targeting on a national scale. Poor access has been be tackled by the Affordable Medicines Facility-malaria (AMFm), an initiative which distributed subsidised ACTs through public and private facilities and retail drug shops. Targeting has been addressed through introducing rapid diagnostic tests (RDT) in public health facilities.
This research has evaluated both AMFm and the roll-out of RDTs in three rural Tanzanian regions, comparing the situation “before and after” the interventions were implemented. We have used surveys of public health facilities, private antimalarial outlets and households. Through these we have assessed the impact on availability, affordability and quality of treatment, as well as coverage at a community level.
In addition, we conducted a cluster randomised controlled trial to assess how effective sending SMS messages to drug shop staff was in improving the way patients took their ACT medication (known as patient adherence).
Finally, we have used qualitative methods to explore the socio-cultural context and other factors that influence the implementation and outcome of the two interventions.
Ifakara Health Institute:
London School of Hygiene & Tropical Medicine
US Centers for Disease Control and Prevention
Katia Bruxvoort, Admirabilis Kalolella, Happy Nchimbi, Charles Festo, Mark Taylor, Rebecca Thomson, Matthew Cairns, Julie Thwing, Immo Kleinschmidt, Catherine Goodman and S. Patrick Kachur | Published
Tropical Medicine and International Health
Sarah Tougher, the ACTwatch Group, Yazoume Ye, John H Amuasi, Idrissa A Kourgueni, Rebecca Thomson, Catherine Goodman, Andrea G Mann, Ruilin Ren, Barbara A Willey, Catherine A Adegoke, Abdinasir Amin, Daniel Ansong, Katia Bruxvoort, Diadier A Diallo, Grac | Published
Katia Bruxvoort, Catherine Goodman, S. Patrick Kachur, David Schellenberg | Published
Melissa A. Briggs, Admirabilis Kalolella, Katia Bruxvoort, Ryan Wiegand, Gerard Lopez, Charles Festo, Pierre Lyaruu, Mitya Kenani, Salim Abdulla, Catherine Goodman, S. Patrick Kachur | Published
Rebecca Thomson, Charles Festo, Boniface Johanes, Admirabilis Kalolella, Katia Bruxvoort, Happy Nchimbi, Sarah Tougher, Matthew Cairns, Mark Taylor, Immo Kleinschmidt, Yazoume Ye, Andrea Mann, Ruilin Ren, Barbara Willey, Fred Arnold, Kara | Published
Joanna R, Deborah D, Lindsay M, Evelyn A, Sham L, Hilda M, Katia B, Jayne W, Lasse V, Shunmay Y, Toby L, Eleanor H, Hugh R, David L, David S, Bonnie C, Sarah S, Virginia W, Catherine G, Clare C | Published
Barbara A Willey, Sarah Tougher, Yazoume Ye, The ACTwatchGroup, Andrea G Mann, Rebecca Thomson, Idrissa A Kourgueni, John H Amuasi, Ruilin Ren, Marilyn Wamukoya, Sergio Torres Rueda, Mark Taylor, Moctar Seydou, Samuel Blay Nguah, Salif Ndiaye, Blessing Mb | Published
Katia Bruxvoort, Charles Festo, Admirabilis Kalolella, Matthew Cairns, Peter Lyaruu, Mitya Kenani, S. Patrick Kachur, Catherine Goodman, David Schellenberg | Published
American Journal of Tropical Medicine and Hygiene
Sarah Tougher, Andrea G. Mann, ACTwatch Group, Yazoume Ye, Idrissa A. Kourgueni, Rebecca Thomson, John H. Amuasi, Ruilin Ren, Barbara A. Willey, Daniel Ansong, Katia Bruxvoort, Graciela Diap, Charles Festo, Boniface Johanes, Admirabilis Kalolella, Oumarou | Published
Katia Bruxvoort, Admirabilis Kalolella, Matthew Cairns, Charles Festo, Mitya Kenani, Peter Lyaruu, S Patrick Kachur, David Schellenberg, Catherine Goodman | Published
Katia Bruxvoort, Charles Festo, Matthew Cairns, Admirabilis Kalolella, Frank Mayaya, S. Patrick Kachur, David Schellenberg, Catherine Goodman | Published
Poyer S, Shewchuk T, Tougher S, Ye Y; ACTwatch Group, Mann AG, Willey BA, Thomson R, Amuasi JH, Ren R, Wamukoya M, Taylor M, Nguah SB, Mberu B, Kalolella A, Juma E, Festo C, Johanes B, Diap G, Bruxvoort K, Ansong D, Hanson K, Arnold F, and Goodman C. | Published
Tropical Medicine & International Health
Clare I.R. Chandler*, Helen Burchett, Louise Boyle, Olivia Achonduh, Anthony Mbonye, Deborah DiLiberto, Hugh Reyburn, Obinna Onwujekwe, Ane Haaland, Arantxa Roca-Feltrer, Frank Baiden, Wilfred F. Mbacham, Richard Ndyomugyenyi, Florence Nankya, Lindsay Man | Published
Health Systems and Reform