Convincing fake antimalarials are a major public health disaster in many regions.
This has led to deaths from malaria and to inaccurate reports of artemisinin resistance. During the lifetime of the ACT Consortium, we had insufficient information on the scale of this problem in most malaria-affected areas, but it was expected to spread globally.
In Africa, antimalarial drugs were frequently of poor quality or expired, although fake antimalarials (in which there are usually no active ingredients) were less common. Unless easily affordable (i.e. heavily subsidised) ACTs are provided through both public and private outlets, it seemed likely that fake ACTs would penetrate markets rapidly as the demand for ACTs increases.
Research questions addressed by the consortium